Research progress on the function and molecular regulation of Bcl-6 in follicular helper T cells
HE Lan1， WANG Meng2， JIANG Hao3
(1.School of Biomedical Sciences， Hunan Provincial Key Laboratory of Medical Virology， Hunan University， Changsha 410012， China； 2. Institut Pasteur of Shanghai， Chinese Academy of Sciences， University of Chinese Academy of Sciences， Shanghai 200031， China； 3. School of Life Sciences， Central South University， Changsha 410006， China)
Abstract：Bcl-6 is the master regulator of follicular helper T cells (Tfh)， which plays a key role in the differentiation and functional regulation of Tfh cells. The specific mechanisms of Bcl-6 regulation of Tfh cells and its precise molecular regulation have been extensively studied. At present， considerable progress has been made. In this paper the research history of Bcl-6 being identified as the master regulator of Tfh is reviewed， and the functions of Bcl-6 in Tfh cells and the research progress of mechanisms of Bcl-6 regulation in Tfh are summarized. The potential problems and future research directions of Bcl-6 are prospected.
何 岚,王 猛,姜 浩. Bcl-6对滤泡辅助性T细胞的调控作用及机制进展[J]. 华中师范大学学报(自然科学版), 2022, 56(4): 670-675.
HE Lan,WANG Meng,JIANG Hao. Research progress on the function and molecular regulation of Bcl-6 in follicular helper T cells. journal1, 2022, 56(4): 670-675.
2022, Vol. 56 
