Abstract：A varieties of squaric acid diesters are prepared by the reactions of squaric acid and correspording alcohols with different alkanes. Follow them, by the reaction with (1S,2R)-(+)- or (1R,2S)-(-)-2-amino-1,2-diphenylalcohol, the C-3 chiral squaric acid amidoalcohols with alkoxyl are synthesized. The chiral squaric acid amidobutyl ester can be hydrolysis or reacted with NaHS to form the C-3 squaric acid amidoalcohols of with OH or SH respectively. The chiral oxazaborolidines that formed by the reaction of the new ligands above with borane can be used in the asymmetry catalytic reaction prochiral ketones. The structures of all the new ligands are affirmed by IR, 1 H NMR, MS and elemental analysis.
收稿日期: 2001-03-25
引用本文:
吕守茂,周海兵,谢如刚. 手性方酰氨基醇配体的设计合成[J]. , 2001, 40(3): 0-0.
吕守茂,周海兵,谢如刚. Syntheses of new chiral squaric acid amides. , 2001, 40(3): 0-0.
